Hyperbaric oxygen enhances tumor penetration and accumulation of engineered bacteria for synergistic photothermal immunotherapy
Abstract Bacteria-mediated cancer therapeutic strategies have attracted increasing interest due to their intrinsic tumor tropism.However, bacteria-based drugs face several challenges including the large size of bacteria and dense extracellular matrix, limiting their intratumoral delivery 3 nef runes efficiency.In this study, we find that hyperbaric